He was educated in the private school of Shepard Johnson, and in September 1837, entered the Freshman Class of Columbia College.  In that Institution he spent one year, and then, in September 1838, entered the Sophomore Class of the University of the City of New York, which had then only lately been established as the germ from which was destined to spring in later years the  present New York University.  He completed his course in the University, and in June 1841, was graduated with the degree of Bachelor of Arts.  He then entered the law office of the Hon. Seth P. Staples as a student, and in January 1845, was admitted to practice at the Bar.  He opened an office in New York, with the Hon Benjamin Nicoll, and began a prosperous career as a lawyer.

John had an active law practice and extensive real estate interests. 

As a young man, he remained abroad six years, explored every country in Europe and the Levant, and extended his journey to India, in which country he spent two years, returning to Europe by way of the Cape of Good Hope.  The journal of this tour was published in two editions in 1859 and 1860, under the title of "WALL STREET TO CASHMERE".

He married Adelia Duane Pell December 22, 1863 at 218 Fifth Ave, New York by Rev. Richard Temple, Rector of Ascension Church, Esopus, New York.

John was active in the development of Greenwich Village to the north of Abington Square.  He was a long time resident of a property he owned on the south side of Washington Square Park which is now a part of New York University.

New York Times October 12, 1913
JOHN B. IRELAND DIES AT 80.  OLD MEMBER OF THE UNION CLUB EXPIRES OF APOPLEXY. 
John B. Ireland, a wealthy real estate owner ond one of the oldest members of the Union League Club, died yesterday at his home, 104 East 73rd Street, of apoplexy at the age of 80.  He was born in Watkins, N.Y. and came to live in this city with his parents when a child.  He was graduated from New York University and after three years study was admitted to the bar in Albany in 1845.  In 1851, Mr. Ireland made a six years tour of the world and wrote a book titled "Wall Street to Cashmere."  Mr. Ireland inherited wealth from his father and devoted his time to managing his big real estate interests.  He was admitted to the Union League Club in 1859 and was also a member of the Sons of the Revolution, St. Nicholas Society and Church Club.  He leaves three sons and three daughters.